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North Knox Wellness – Weight Loss Center

Written by Dianne on May 26, 2026 — Medically Reviewed by Dianne

Weight Loss Clinic

Clinic Information

Clinic Name: North Knox Wellness
Address: 6523 Central Avenue Pike, Suite 108, Knoxville, TN 37912
Phone: (865) 357-5377
Website: https://northknoxwellness.com/ 

Overview

North Knox Wellness is a wellness and spa that provides either medically supervised weight loss or holistic wellness in Knoxville, Tennessee. In order to enhance both your well-being and self-confidence, they provide a diverse range of services including hormonal therapy, IV hydration, injectables (Botox, etc.), chemical peel treatments, microneedling, and facial rejuvenation as a holistic approach to health.

With the goal of improving your long-term, overall health by designing individualised wellness plans for each patient incorporating the patient’s goals into their plan, the clinic focuses on a collaborative model of patient care. By working with the patient to develop a long-term plan, the clinic is also able to assist in achieving the patient’s wellness goals through lifestyle modifications.

Medical Director

Trent W. Cross M.D., who graduated from the University of Tennessee Memphis with his MD in 2003 and completed his internal medicine residency at the University of Tennessee Knoxville in 2006, is the clinic’s medical director and chief. Having been involved with internal medicine for over 20 years and having been involved with multiple different areas within the field over that time, Dr. Cross is well equipped to blend the clinic’s philosophy of comprehensive wellness with its commitment to preventive health and healing.

GLP-1 and Medical Weight Loss Programs

North Knox Wellness provides a variety of medical weight-loss programs that aim to support healthy and sustainable weight loss. This includes prescription appetite suppressants, vitamin injections, metabolism-boosting treatments, and GLP-1 medications (e.g., Semaglutide, Tirzepatide, Dulaglutide, and Liraglutide). The weekly injections enable patients to feel fuller longer, help regulate insulin response, and help to slow stomach emptying; this can lead to extensive weight-loss results when combined with lifestyle changes.

The clinic has additional support through B-12 injections, Mega-Burn injections, metabolism boosters, and nutritional supplements (e.g., Lipo-BC). For patients preferring more traditional medical weight-loss drugs, Phentermine and Topiramate are available with provider supervision. 

Weight Loss Program Pricing

North Knox Wellness provides several wellness treatments on their website, including pricing. For example, the SkinPen Precision Microneedling starts out at $250 for each session and $700 for three sessions. The price of the SkinPen with PRP is $450 with package pricing available for multiple sessions. However, specific pricing for GLP-1 injections and prescription weight-loss medications is not fully listed online as they depend on dosage and type of medication and specific treatment plan; therefore, patients must contact the clinic.

Patient Reviews

The overall reaction from North Knox Wellness patients from Google and Yelp has been that this is a very supportive, individualized environment that makes it easy for their patient to succeed. Most patients who have used the facilities comment on how much they appreciate the highly individualized weight-loss recommendations and the many other services RNW provides for total wellness. There are many comments on the internet in regard to weight loss offices in Knoxville that stress how important it is to use medically supervised weight loss programs, provide an individualized weight loss plan, and provide continued support in order to achieve long-term success.

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6523 Central Avenue Pike, Suite 108, Knoxville, TN 37912

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