John Alverdy

Reported credentials

• Surgery Source ↗

Source-reported information; confirm current details directly.

Selected publications

• The Microbiome in Critical Illness. · 2026 Source ↗
• Post-COVID impairment of T cell responses to community-acquired pathogens can be modified by activating cellular metabolism. · 2026 Source ↗
• Nasogastric Tubes-Indications, Placement, and Management: A Review. · 2026 Source ↗
• Microbiota-accessible carbohydrates enhance gut microbiota stability and antibiotic resilience through production of quorum sensing molecule AI-2. · 2026 Source ↗
• Non-antibiotic management of bacterial keratitis. · 2026 Source ↗
• Feasibility and preliminary results of modeling a clinically meaningful anastomotic leak in pigs. · 2026 Source ↗
• Invited commentary on "Gut microbiome and metabolome profiling in obesity reveals an association between the effectiveness of sleeve gastrectomy and the composition and function of the gut microbiome". · 2025 Source ↗
• Surgical advocacy as an academic career path: A guide for promotion discussions. · 2025 Source ↗
• Friend or foe: the gut microbiota as a modulator of disease trajectory in trauma, surgery, and critical illness. · 2025 Source ↗
• Preparing the Bowel for Surgery in the Era of Microbiome Sciences. · 2025 Source ↗
• The Scientific Rationale for Diversity, Equity, and Inclusion: Nature-inspired Design. · 2026 Source ↗
• Dietary impact on the gut resistome: western diet independently increases the prevalence of antibiotic resistance genes within the gut microbiota. · 2025 Source ↗
• The multifaceted role of sirtuins in inflammatory bowel diseases. · 2025 Source ↗
• Unpacking the sepsis controversy. · 2025 Source ↗
• Misapplication of Biologic Mesh in Clean-Site Elective Ventral Hernia Repair. · 2025 Source ↗
• Enterobactin inhibits microbiota-dependent activation of AhR to promote bacterial sepsis in mice. · 2025 Source ↗
• Invited commentary: human effluvia, microbiome-based biomarkers and cancer screening. · 2025 Source ↗
• U-Type-Shaped Curves Across Economics, Biology, and Infection. · 2025 Source ↗
• Enhancing equity in academic surgery promotion practices. · 2025 Source ↗
• The Combined Effect of Western Diet Consumption and Diclofenac Administration Alters the Gut Microbiota and Promotes Anastomotic Leakage in the Distal Colon. · 2024 Source ↗
• Invited Commentary: Neurocognitive Testing, Retirement, and Self-Awareness: It Is Just Another Judgment Call. · 2024 Source ↗
• Bowel cleansing, dysbiosis, and postoperative infection: the dots are starting to connect. · 2024 Source ↗
• Preventing Surgical Site Infections in the Era of Escalating Antibiotic Resistance and Antibiotic Stewardship. · 2024 Source ↗
• Where do the pathogens that cause surgical site infections come from? · 2024 Source ↗
• IDEAL Phase 2a Results: Posterior Rectus Sheath Flap for Hiatal Augmentation in Complex Paraesophageal Hernias. · 2024 Source ↗
• Social determinants of health, the microbiome, and surgical injury. · 2024 Source ↗
• Comment on: Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries. · 2024 Source ↗
• Commentary on: Role of Microbiome in the Outcomes Following Surgical Repair of Perianal Fistula: Prospective Cohort Study Design and Preliminary Results. · 2023 Source ↗
• Expert Commentary on Perioperative Malnutrition. · 2023 Source ↗
• Invited Commentary: Scientific Rationale behind Intestinal Alkaline Phosphatase Administration to Enhance Recovery after Pancreaticoduodenectomy. · 2024 Source ↗
• Studies Involving Surgical Site Infections (SSIs) Without Culture Results, the Antibiotics Chosen for Prophylaxis and Antibiotic Sensitivity Data: "Are they Actionable?" · 2024 Source ↗
• Peptide YY: A Paneth cell antimicrobial peptide that maintains <i>Candida</i> gut commensalism. · 2023 Source ↗
• The role of dietary prehabilitation on anastomotic healing. · 2023 Source ↗
• Western Diet-induced Transcriptional Changes in Anastomotic Tissue Is Associated With Early Local Recurrence in a Mouse Model of Colorectal Surgery. · 2023 Source ↗
• What Is the Role of the Gut in Wound Infections? · 2023 Source ↗
• To Operate or Not? Balancing Advanced Imaging, Machine Learning, and the Doctor-Patient Relationship in Complex Clinical Decision Making. · 2023 Source ↗
• Rationale for Colonic Pre-Habilitation Prior to Restoration of Gastrointestinal Continuity. · 2023 Source ↗
• Biologically inspired gastrointestinal stapler design: "Getting to Zero" complications. · 2023 Source ↗
• "It Is Not Necessary to Kill Them in Order to Make Them Relatively Harmless": Molecular Diplomacy in the Pathogen-Host Interaction. · 2023 Source ↗
• The Role of the Gut Microbiome on the Development of Surgical Site Infections. · 2023 Source ↗
• Pitfalls and Traps in the Surgical Evaluation of Patients with Irritable Bowel Syndrome (IBS). · 2023 Source ↗
• Association Does Not Equal Causation-Does Thinking You Are Better Make You Better? · 2022 Source ↗
• Rationale behind phosphate therapy to modulate the gut microbiome and protect against surgery-related infection. · 2023 Source ↗
• Defeating Cancel Culture in Surgical Site Infection Research: A Plea to Include Microbial Cultures and Antibiotic Sensitivity Data. · 2022 Source ↗
• Emerging Paradigms in the Prevention of Surgical Site Infection: The Patient Microbiome and Antimicrobial Resistance. · 2022 Source ↗
• A Novel Nonantibiotic Gut-directed Strategy to Prevent Surgical Site Infections. · 2022 Source ↗
• <i>Letter to the Editor:</i> Between-Group Comparison Fallacy. · 2022 Source ↗
• Misinformation About the Human Gut Microbiome in YouTube Videos: Cross-sectional Study. · 2022 Source ↗
• Surgeons, Infectious Diseases, and Twitter Hit a Home Run for Antibiotic Stewardship. · 2022 Source ↗
• Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells. · 2022 Source ↗
• Case presentation and panel discussion: Critical illness. · 2021 Source ↗
• Autologous Posterior Rectus Sheath as a Vascularized Onlay Flap: a Novel Approach to Hiatal Hernia Repair. · 2022 Source ↗
• Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation: A Practical Solution to a Complex Problem. · 2021 Source ↗
• Influence of the Microbiome on Anastomotic Leak. · 2021 Source ↗
• Re-examining chemically defined liquid diets through the lens of the microbiome. · 2021 Source ↗
• Anastomotic Leak: Toward an Understanding of Its Root Causes. · 2021 Source ↗
• <i>Enterococcus faecalis</i> Is Associated with Anastomotic Leak in Patients Undergoing Colorectal Surgery. · 2021 Source ↗
• Sepsis and the Microbiome: A Vicious Cycle. · 2021 Source ↗
• Harnessing the Microbiome to Optimize Surgical Outcomes in the COVID-19 Era. · 2021 Source ↗
• Patient Acceptance of Routine Serial Postoperative Endoscopy Following Low Anterior Resection (LAR) and Its Ability to Detect Biomarkers in Anastomotic Lavage Fluid. · 2021 Source ↗
• Peer Review and the Quest for Technical Excellence in Surgery-A Lesson in Self-awareness. · 2021 Source ↗
• The Benefits of Robotic Surgery: Are They Technical or Molecular? · 2021 Source ↗
• Defining Microbiome Readiness for Surgery: Dietary Prehabilitation and Stool Biomarkers as Predictive Tools to Improve Outcome. · 2022 Source ↗
• Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate. · 2021 Source ↗
• Surgical site infections following elective surgery - Authors' reply. · 2020 Source ↗
• Can the Cecal Ligation and Puncture Model Be Repurposed To Better Inform Therapy in Human Sepsis? · 2020 Source ↗
• Letter to a Young Surgeon During Coronavirus Disease 2019. · 2020 Source ↗
• The use of fecal microbiota transplant in sepsis. · 2020 Source ↗
• Comparative genetics of Enterococcus faecalis intestinal tissue isolates before and after surgery in a rat model of colon anastomosis. · 2020 Source ↗
• Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. · 2020 Source ↗
• Spatial Compartmentalization of the Microbiome between the Lumen and Crypts Is Lost in the Murine Cecum following the Process of Surgery, Including Overnight Fasting and Exposure to Antibiotics. · 2020 Source ↗
• Is bariatric surgery resolving NAFLD via microbiota-mediated bile acid ratio reversal? A comprehensive review. · 2020 Source ↗
• Involvement of the Commensal Organism <i>Bacillus subtilis</i> in the Pathogenesis of Anastomotic Leak. · 2020 Source ↗
• An in vitro tissue model for screening sustained release of phosphate-based therapeutic attenuation of pathogen-induced proteolytic matrix degradation. · 2020 Source ↗
• The Biology of Anastomotic Healing-the Unknown Overwhelms the Known. · 2020 Source ↗
• Re-examining causes of surgical site infections following elective surgery in the era of asepsis. · 2020 Source ↗
• Preparing the bowel for surgery: rethinking the strategy. · 2019 Source ↗
• <i>Enterococcus faecalis</i> exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets. · 2020 Source ↗
• Western Diet Promotes Intestinal Colonization by Collagenolytic Microbes and Promotes Tumor Formation After Colorectal Surgery. · 2020 Source ↗
• Infliximab Does Not Promote the Presence of Collagenolytic Bacteria in a Mouse Model of Colorectal Anastomosis. · 2020 Source ↗
• Mice Fed an Obesogenic Western Diet, Administered Antibiotics, and Subjected to a Sterile Surgical Procedure Develop Lethal Septicemia with Multidrug-Resistant Pathobionts. · 2019 Source ↗
• Identification of Collagenolytic Bacteria in Human Samples: Screening Methods and Clinical Implications for Resolving and Preventing Anastomotic Leaks and Wound Complications. · 2019 Source ↗
• Sustained Release of Phosphates From Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation <i>in vitro</i>. · 2019 Source ↗
• Surgeon as Basic Bench Scientist: A Play in Three Acts. · 2019 Source ↗
• International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis. · 2019 Source ↗
• The wound environment, microbial virulence and postoperative infection: Practical lessons for the surgeon. · 2018 Source ↗
• Oral Polyphosphate Suppresses Bacterial Collagenase Production and Prevents Anastomotic Leak Due to Serratia marcescens and Pseudomonas aeruginosa. · 2018 Source ↗
• Ionic Modulation of Bacterial Virulence and Its Role in Surgical Infection. · 2018 Source ↗
• Microbiome Medicine: This Changes Everything. · 2018 Source ↗
• Hypermetabolism and Nutritional Support in Sepsis. · 2018 Source ↗
• Media from macrophages co-incubated with Enterococcus faecalis induces epithelial cell monolayer reassembly and altered cell morphology. · 2017 Source ↗
• De Novo Synthesis of Phosphorylated Triblock Copolymers with Pathogen Virulence-Suppressing Properties That Prevent Infection-Related Mortality. · 2017 Source ↗
• Optimum Operating Room Environment for the Prevention of Surgical Site Infections. · 2017 Source ↗
• Preparing the Bowel for Surgery: Learning from the Past and Planning for the Future. · 2017 Source ↗
• The Influence of Host Stress on the Mechanism of Infection: Lost Microbiomes, Emergent Pathobiomes, and the Role of Interkingdom Signaling. · 2017 Source ↗
• Stochasticity among Antibiotic-Resistance Profiles of Common Burn-Related Pathogens over a Six-Year Period. · 2017 Source ↗
• Bacterial colonization and succession in a newly opened hospital. · 2017 Source ↗
• Smoking and Postoperative Surgical Site Infection: Where There's Smoke, There's Fire. · 2017 Source ↗
• Collapse of the Microbiome, Emergence of the Pathobiome, and the Immunopathology of Sepsis. · 2017 Source ↗
• Critical role of microbiota within cecal crypts on the regenerative capacity of the intestinal epithelium following surgical stress. · 2017 Source ↗
• Characteristics and Outcomes of Complicated Intra-abdominal Infections Involving Pseudomonas aeruginosa from a Randomized, Double-Blind, Phase 3 Ceftolozane-Tazobactam Study. · 2016 Source ↗
• A Video Is Worth a Thousand Words. · 2016 Source ↗
• Morphine Promotes Colonization of Anastomotic Tissues with Collagenase - Producing Enterococcus faecalis and Causes Leak. · 2016 Source ↗
• De Novo Synthesis and Functional Analysis of Polyphosphate-Loaded Poly(Ethylene) Glycol Hydrogel Nanoparticles Targeting Pyocyanin and Pyoverdin Production in Pseudomonas aeruginosa as a Model Intestinal Pathogen. · 2017 Source ↗
• The gut microbiota and gastrointestinal surgery. · 2017 Source ↗
• The intestinal microbiome and surgical disease. · 2016 Source ↗
• Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility. · 2016 Source ↗
• Prevention of Perioperative Anastomotic Healing Complications: Anastomotic Stricture and Anastomotic Leak. · 2016 Source ↗
• C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype. · 2016 Source ↗
• Stool consistency as a major confounding factor affecting microbiota composition: an ignored variable? · 2016 Source ↗
• Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak. · 2015 Source ↗
• Membership and behavior of ultra-low-diversity pathogen communities present in the gut of humans during prolonged critical illness. · 2014 Source ↗
• Valuable heartburn data that may be difficult to swallow. · 2015 Source ↗
• The opposing forces of the intestinal microbiome and the emerging pathobiome. · 2014 Source ↗
• Intestinal anastomotic injury alters spatially defined microbiome composition and function. · 2014 Source ↗
• Proceedings of the 2013 A.S.P.E.N. Research workshop: the interface between nutrition and the gut microbiome: implications and applications for human health [corrected]. · 2014 Source ↗
• The Hospital Microbiome Project: Meeting report for the 2nd Hospital Microbiome Project, Chicago, USA, January 15(th), 2013. · 2013 Source ↗
• During critical illness the gut does not pass the acid test. · 2012 Source ↗
• Stapling and sleeve: science and myths. · 2010 Source ↗
• Bariatric surgery: a history of empiricism, a future in science. · 2009 Source ↗
• The re-emerging role of the intestinal microflora in critical illness and inflammation: why the gut hypothesis of sepsis syndrome will not go away. · 2008 Source ↗
• NOTES: a surgeon's perspective. · 2007 Source ↗
• The impact of stress and nutrition on bacterial-host interactions at the intestinal epithelial surface. · 2005 Source ↗
• Influence of the critically ill state on host-pathogen interactions within the intestine: gut-derived sepsis redefined. · 2003 Source ↗

Source-reported information; confirm current details directly.

Insurance reported

Reported in source records. Confirm the exact plan, network and procedure with the practice and insurer. Logos identify brands; they do not establish participation.